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 |   Related post: tion at the head of the therapeutic means available in the treatment of the manifold dyspeptic conditions. The explanation of how the current exercises its curative effect has a merely theoretical interest. In regard to the practical use and value of a certain remedy, it can be at present estimated by empirical results alone. This being obtained in numerous eases by various au- thors, and being favorable, the remedy will have to be pronounced useful, otherwise not. The reports on intragastric electrization which have of late been published are quite numerous and very favorable. This mode of treatment is, therefore, of great value and deserves to be still more promulgated than it thus far has been. That old, well-recognized remedies which have stood the test of experience are occasionally repudiated by physiological experiments is an occurrence which has been of late frequently observed. I need only mention, as an instance, the effect upon the stomach of the bitter remedies (amara), which has been refuted by the experi- ments of Tschelzoff on dogs and of JaworsM on human beings. Notwithstanding this, the " amara " continue to be used, and I should not be astonished if new Primaquine Cost experi- ments, arranged somewhat differently, should prove the efficacy of this class of remedies and obtain for them warm advocates. ' Although I am, myself, an ardent believer in ex- perimental investigation, I am, nevertheless, of the opin- ion that old facts should not be so quickly upset. If we now again turn to direct electrization of the stomach, we find that an important investigator has recently written against this therapeutic means, basing his views entirely upon experiments made on animals. I mean Dr. S. J. Meltzer.* Intragastric electrization being of Primaquine Tablets practical importance and high value, I Primaquine Phosphate consider it opportune to enter upon a discussion of this subject. In his paper, An Experimental Study of Direct and Indirect Faradization of the Digestive Canal in Dogs, Cats, and Rabbits, Meltzer arrives at the following con- clusions: " The mucous membrane of the digestive canal offers a considerable resistance to the penetration of the faradaic current Buy Primaquine to the muscular coat; the great- est resistance is found in the mucous membrane of the stomach. The percutaneous and the direct faradization of the stomach or the intestines can not produce any contraction in these parts. " My statements have reference only to the animals I experimented with. However, abdominal surgery might offer an opportunity to test their validity for the human being." , In perusing Dr. Meltzer's paper the following three points are somewhat startling: 1. In studying direct electrization cf the stomach on animals — in which one electrode was situated within the viscus, the other at the serosa — this investigator did not * S. J. Meltzer. New York Medical Journal, June 16, 1S95 780 EINUORN: DIRECT ELECTRIZATION OF THE STOMAOH. [N. Y. Med. Joub., get any contraction whatever of the stomach, even if the faradaic current was very strong and if the two elec- id« were not very far apart. (If the electrodes were directly opposite each other, then a strong current pro- duced weak contraction. 2. In faradizing the gastric serosa with a bipolar elec- trode, Meltzer produced contractions only in the pyloric portion of the stomach, whereas the fundus of the organ remained inert even when the current was very strong. 3. The resistance of the gastric mucosa, according to Meltzer, is different from that of all other mucous membranes, being here very great. While the first two points have direct reference to experiments on animals, the accuracy of which can only be ascertained by similar trials on animals, the third point is merely theoretically constructed, and, as it ap- pears to me, on a false basis. In contrast to Meltzer's experiments on animals I will report some of my own investigations, which I copy from my record book. Experiment I ; July 2, 1895. — Frog fastened with nails to a board; abdomen opened. Stomach filled with Related links: Hyaluronic Acid Acne, Valtrex 500 Mg Caplet, Tylenol Price, buy zithromax online no prescription, retin-a generic no prescription, zoloft online pharmacy, cheap exelon patch, buy zithromax, Minoxidil 15 Azelaic Acid, Ditropan Online
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