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Related post: tient was not willing to continue the treatment. After the no-
dosities disappeared he came back and the treatment was re-
sumed.
He had found, contrary to what had been said in the books,
that a small quantity of corrosive sublimate would not remove
the symptoms, particularly in cases of tuberculous skin disease
in the form complicated with ulceration. One had to use many
injections before any effect on the ulceration was produced.
Finally, the ulcerations disappeared as a rule. The great
advantage of the use of injections was that it overcame
the great tediousness of the ordinary treatment and the lia-
bility of the production of digestive disturbances. In a case
he had in mind a man was in splendid general health while
the hypodermic method was used, but when mercury was used
by the mouth he suffered from diarrhcea and troubles with the
stomach.
He had not used injections in the primary stage of syphilis,
but in one case he had used them immediately on the appear-
ance of the secondary symptoms. After the use of twelve in-
jections the symptoms disappeared, but they reappeared in the
course of a month in a rather unusual form — that of thickening
of the nails. He was now using injections in this case. The
general health was excellent, although the patient had been
much run down before. The pain, while it was sometimes se-
vere, was not unbearable.
Dr. J. A. Cantrell thought that the hypodermic treatment
of syphilis would cure in most of the cases. He had seen forty
or fifty cases where the treatment had been continued up to
thirty or thirty-five injections, and where the patients Mesterolone Tablets had not
come back for the treatment of the disease. He had seen one
of these cases seven years after the treatment, and there had
been no return of the disease. He had, however, seen cases
where the injections had been continued until as many Mesterolone Online as sixty
or even a hundred and twenty had been given without benefit.
Fournier had, he believed, within a month injected for macular
syphiloderm. Sometimes the injections Generic Mesterolone were not absorbed for
a week or ten days, and often left decided ulceration. In the
cases Buy Mesterolone in which he had seen the method employed he thought
that it would have been better to use internal treatment, and if
the cases did not do well the hypodermic method might have
been tried.
Dr. EowrN Rosenthal had used hypodermic injections of
corrosive sublimate quite a number of times. He thought that
Dr. White had been too severe in his denunciation of this
method of treating syphilis. Practical experience had demon-
strated its utility and the many advantages it had over other
methods. The inunction method, for instance, was the dirtiest
that could be employed, and would drive away more patients
than the hypodermic method would. One of the points in favor
of the latter method was that the patient had nothing to do
with the treatment, but ate and drank while imdergoing a cure.
The injections were cleanly and devoid of all risk when judi-
ciously made; at first they were made daily, and afterward
every second or third day.
He had given the injections in the primary disease, in a case
of chancre of the tongue, in which the lymphatic glands in the
cervical region were very much enlarged, and where the inter-
nal administration of remedies could not be borne by the pa-
AprU 15, 1893.]
PROCEEDINGS OF SOCIETIES.
423
tient and prompt treattnent was indicated, with very good re-
sults. This patient was still under treatment, but there had
been no appearance of an eruption.
Speaking of the large dose given at a single injection and its
good results, he wished to record another point, and that was:
In infantile syphilis the dose of j^ or y^ grain of corrosive
sublimate, as recommended by Dr. Jacobi {Journal of Padi-
atrics), was too small. He had seen a vast number of cases of
infantile syphilis, and had lost quite a number of patients until
he had increased the dose; and he now never began with less
than -j-'j grain of corrosive sublimate, and gradually increased
the dose.
Dr. Charles Wirgman thought that a point to be borne in
mind, both in private and in hospital practice, was that as soon
as the lesions disappeared the patient ceased to return for
treatment. No matter how eloquent one might be in regard to
the necessity of continuing treatment, they disappeared. If it
could be demonstrated by a more extensive use of this method
that thirty-five, seventy-five, or even one hundred and seventy-
five injections would take the place of two or three years' treat-
ment, that would be a great boon to humanity, and the question
was worthy of serious consideration and further trial.
Dr. S. SoLis-CoHES thought the discussion pointed to the

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